Saurav Raj

4 Questions 4 Answers 0 Followers

Questions related from Saurav Raj

What are the different key steps to do/follow while packing silica column in hexane such that there is no column break during Column Purification?

I usually make silica slurry in hexane and after a good mixture of silica and hexane, I pack the column, and finally use an air-pressure pump to pack the column well? However, sometimes the column...

03 September 2021 9,079 3 View

What is the role of ether solvent (such as THF) in Sonogashira coupling?

Can Amine (such as Et3N) be used as solvent as well as base for the Sonogashira Coupling? How to decide the amount of solvent to be used in any reaction? Does the amount of solvent affect the...

15 February 2021 4,215 3 View

Why in Suzuki Coupling, only weak bases like sodium carbonate, potassium carbonate, etc. are used, and not the strong bases like NaOH ?

Base in the Suzuki coupling has very critical role. So, when we see in general any Suzuki Coupling weak bases are used. Please explain the answer ?

16 July 2019 4,008 2 View

What is the role of nitrobenzene in the synthesis of 1,3,6,8-tetrabromopyrene ?

During the synthesis of 1,3,6,8-tetrabromopyrene, nitrobenzene was used as solvent, so I feel that it was used as a solvent may be because the reaction requires high temperature to form the...

04 July 2019 2,643 3 View