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On inducing the mouse bone marrow cells with X compound, there is a change in cells morphology and characteristics. In that case how to gate these cells, as these cells are showing suppressive...
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High NO secretion by Dendritic cells makes cell suppressive. As NO is known to induce the pro inflammatory cytokines. But high level of NO leads to decrease in secretion of pro inflammatory...
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DC on my compound treatment is secreting high amount of NO, and it is well known that it leads to the nitrosylation of TCR on T cells. So, is there any in vitro method to check it.
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