Sairaj Satarker

5 Questions 8 Answers 0 Followers

Questions related from Sairaj Satarker

Which is the best method of preparation of nanoparticles containing amino acids?

Hi, I would like to know the best method of preparing nanoparticles containing amino acids. I have tried nanoprecipitation method but the entrapment efficiency is very low.

29 June 2023 7,006 3 View

After how many days of I.C.V infusion of amyloid beta 1-42 in rats can we evaluate cognitive decline in Morris Water Maze?

I am trying to develop amyloid beta 1-42 i.c.v model in rats. Can anyone suggest after how many days of infusion can I subject the animals to Morris Water Maze to evaluate cognitive decline? Also...

12 July 2021 1,120 2 View

Can we use DMEM instead of Hams F12 Phenol free culture media for oligomerization of amyloid beta 1-42?

I am trying to form amyloid beta 1-42 oligomers for i.c.v injection in rats. As per WB. Stine protocol use of Hams F12 culture media is recommended but I am facing availability issues. Can I use...

22 April 2021 4,132 7 View

Which is the best way to process Amyloid Beta 1-42 oligomers for inducing cognitive deficits in rats?

I am trying to simulate AD conditions in rats using Amyloid Beta 1-42 oligomers for which I would like to know the best methods for its processing. I have read about the use of...

07 March 2020 4,391 3 View

Which is the best way to induce Alzheimer's disease pathology in rats?

I am trying to develop an efficient and an effective AD model using Wistar rats.I require suggestions as to which model may be the best one to mimic AD pathology in rats. The one that comes to my...

14 December 2019 8,958 4 View