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Questions related from Saidhbhe L. O'Riordan
Numerous dyes available. Need a recommendation for a stable (~1-2 hrs) sensitive (sub-micromolar) dye in-vitro. Looking to measure enzymatic production of hydrogen peroxide from an oxidase enzyme,...
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Does drug glucuronidation over a number of days change in response to continual administration at the same dose and frequency?. Looking for any literature evidence supportive or to the contrary.
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Is it possible to measure how much of a drug has been converted to drug-gluconoride by the liver. I do not have drug levels in the blood or metabolite in urine.
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What is the simplest, benchtop way, to find out the proportion of a drug bound to protein in the brain following systemic treatment in vivo?
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