Sabarinathan Rangasamy

11 Questions 14 Answers 0 Followers

Questions related from Sabarinathan Rangasamy

How to fabricate an organic Field Effect Transistors (OFET)?

I have synthesized a new semiconducting organic material for OFET application. Since I have no hands-on experience in fabrication, I would like to seek your suggestions on following queries: What...

18 November 2016 9,396 6 View

Why does a macrocyclic compound which can be separated by a normal column (manually) was not able to separate or detect any peak by using HPLC?

I tried to purify a highly water soluble compound using RP-HPLC. Unfortunately, no UV peak was detected, however, when a same compound was run on a normal C18 column, there were three different...

17 June 2015 4,974 5 View

How can I calculate singlet oxygen quantum yield of a photosensitizer by using the phosphorescence method?

Please provide me a step by step protocol to measure the quantum yield.

06 May 2015 5,531 1 View

How can I load a non-water soluble aromatic drug molecule on to a graphene oxide?

A well established protocol was followed for drug loading. Unfortunately, the method seems not working. Is it necessary to have drug soluble in DMSO for loading? I tried to load drug by dissolving...

06 May 2015 814 2 View

Why does graphene oxide (GO) gets agglomerated upon addition to sodium hydroxide and chloroacetic acid?

I wanted to conjugate follic acid to GO as per published report. But as I add NaOH and chloroacetic acid to GO suspension it gets agglomerated or precipitated. Is there any procedure that I need...

19 March 2015 5,632 4 View

Do MCF-7 cancer cells activate caspase-3 during apoptosis?

Please suggest me whether MCF-7 cancer cell produce caspase-3 during apoptotic cell death?

30 January 2015 4,033 12 View

How do you detect singlet oxygen and calculate its quantum yield by phosphorescence?

I wanted to measure the quantum yield of singlet oxygen by phosphorescence. In this regard my questions are: 1. How much concentration is required? 2. Do I need to measure both in aerated and...

20 November 2014 3,088 6 View

How to purify a sulfonated porphyrins or the other organic compounds?

I have prepared sulfonated porphyrins and purified by soxhlet extraction. But MALDI-TOF analysis showed other impurities. I would appreciate if you could suggest me some suitable method to purify...

17 September 2014 9,556 5 View

Is chloroform suitable for cell culture experiments?

Please suggest me whether minimal amount of chloroform (0.1%) is suitable to use in cell culture experiments. As my organic compound shows degradation behavior in DMSO solvents, I prefer using an...

21 August 2014 9,666 13 View

How can I measure Laser power using a power meter?

I wanted to measure Laser power for using it in a biological application. I can understand that as the distance of the laser is adjusted, the beam/spot size is also varied and subsequently power...

14 August 2014 4,042 5 View

How to carry out a sulfonation reaction?

I need to carry out sulfonation reaction for heterocyclic compound (Benzo [b] thiophene) using chlorosulfonic acid. I would appreciate if anyone can suggest a suitable protocol to do the reaction...

14 January 2014 4,189 10 View