Ruchi Yadav

3 Questions 7 Answers 0 Followers

Questions related from Ruchi Yadav

How to decide a animal dose from IC50 (Wnt inhibition assay) ?

Through a Wnt inhibition assay, I have found out that my test drug, which is easily available in the market and used for Hyperlipidemia, is a good Wnt inhibitor. Now, I want to conduct an animal...

29 September 2023 3,143 5 View

What is difference between STF and STF3A cells? If I want to find out Wnt inhibitors from these two which cell line will be more useful?

In some papers I find out they are using both the cell lines (STF and STF3A cells) for screening of Wnt inhibitors. Is it okay to use only STF3A cells for screening of Wnt inhibitors?

13 December 2022 2,359 2 View

Is there any alternative assay for TCF/LEF Reporter assay for finding out my drugs are WNT inhibitor or activator ?

I am doing research on WNT Pathway. I have multiple drugs and want to do a assay to find out my drugs are WNT activators or inhibitors. I know about TCF/LEF reporter assay kit. But I do not have...

08 February 2022 1,304 4 View