Reji Joseph

6 Questions 28 Answers 0 Followers

Questions related from Reji Joseph

What is the role of asymptomatic COVID-19 cases in the epidemiology of the disease?

Current evidence suggests that most transmission occurs from symptomatic people through close contact with others. Accordingly, most recommendations by WHO on personal protective measures (such as...

06 July 2020 5,981 2 View

Have any mutations been discovered for SARS-CoV-2, the virus that causes coronavirus disease(COVID-19)?

In early May 2020, a study by Korber et al reported the emergence of a SARS-CoV-2 mutation (Spike D614G), one of several Spike (S) mutations that have been discovered. SARS-CoV-2 infections with...

30 June 2020 9,509 2 View

What is the duration of viral shedding in persons with coronavirus disease CoVID-19?

In a small group of patients with mild COVID-19, nasopharyngeal/oropharyngeal swabs collected during the first week of illness showed infectious virus but not after this period despite high...

24 June 2020 9,413 20 View

What is the host response to SARS-CoV-2 and pathology of COVID-19?

After an initial push to look for therapeutic and vaccine options to help treat and prevent COVID-19, it will be important to better understand the host response to infection and the pathology of...

17 June 2020 1,895 13 View

What precautionary measures should be taken when animals have close contact with humans suspected or confirmed to be infected with SARS-CoV-2?

There is no evidence that companion animals are playing an epidemiological role in the spread of human infections with SARS-CoV-2. However, reports from infected mink farms suggest that in these...

17 June 2020 7,813 3 View

Why is diabetes a risk factor for coronavirus disease 2019 (COVID-19)?

SARS-CoV-2 is known to utilize angiotensin-converting enzyme 2 (ACE2) receptors for entry into target cells. Insulin administration attenuates ACE2 expression, while hypoglycemic agents (eg,...

15 June 2020 6,727 12 View