Raúl Argüello-García

7 Questions 8 Answers 0 Followers

Questions related from Raúl Argüello-García

How can I calculate the antiquity of a gene sequence?

Molecular clocks, fossil records and phylogenetic trees are important resources for this end but these do not look so accesible for direct timing application. I would like to know if there is a...

4 weeks ago 3,801 0 View

What sample is better to characterize gut microbiota?

We are interested in characterizing the microbial populations residing in the intestines of mice subjected to antiparasitic treatment. To analyze gut microbiota, some studies use fecal samples...

11 September 2024 3,844 2 View

Can anybody recommend tips to obtain a PCR product using primers already reported that in our hands fail?

We are interested to analyze the expression of a test gene by Real Time-PCR. Primers and PCR conditions were the same as in a previous paper with the same organism but in our hands the product is...

14 September 2023 1,367 4 View

Can anyone explain how to perform a virtual drug screening in ZINC?

I have the sequence and structure model of a protozoan enzyme and I want to find compounds commercially available in the ZINC12 database that could inhibit this protein. Thanks in advance for your...

18 July 2017 9,664 3 View

Does anybody know how to monitor the stability of a drug in a solution contained in an osmotic mini-pump implanted subcutaneously in rats?

The purpose of the mini-pump is to deliver in a sustained manner the compound known as 7-OHDPAT over a period of 2 months... Thanks in advance for your comments!!

01 June 2016 2,286 2 View

Does somebody know a non-HPLC technique to detect and quantify benzimidazoles and its metabolites (sulphoxide and sulphone)?

I am interested in determining albendazole, albendazole-sulphoxide and albendazole-sulphone levels in cellular extracts. I have the three species in purified form...

08 March 2016 2,268 1 View

Does anybody know a server/platform for quick and high quality protein modeling?

I am interested to obtain protein models for further molecular dynamics studies. I have already used I-Tasser and Robetta servers and in some cases the RMSD values obtained in I-Tasser are too...

01 November 2014 3,610 10 View