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Questions related from Prithvi Singh
I have increased expression of STAT3 in multiple sclerosis (MS) patients as compared to controls. Can Extavia be used as an inhbitor against STAT3 in MS patients? Will it be beneficial to stop the...
26 October 2023 3,045 0 View
I have found a significant gene (BIRC5) between lung cancer tumor and adjacent normal samples. In the literature, it is mentioned that BIRC5 (an anti-apopotic gene) is generally upregulatd is most...
09 December 2022 2,449 1 View
I have some apoptotic proteins identified from breast cancer datasets. I have a general queres in my mind. 1) How does apoptotic proteins function in cancer cells? 2) Would inhibiting an...
22 March 2022 307 4 View
Even though gram-positive bacteria has a thick cell wall than the gram-negative bacteria, then why only gram-negative bacteria are more resistant to antibiotics....
05 November 2018 5,697 9 View
I have a set of genes with expression data and p-values , but i want to know how to calculate Fold change(FC) values for these genes in R or MATLAB without assigning normal and tumor data in any...
24 December 2017 2,588 0 View
I have one illumina beadchip expression data and other being the Agilent microarray data from GEO database. I want to do meta-analysis of these two different datasets based on some kind of...
21 October 2017 9,649 3 View
How can we generate super-enhancer mediated lncRNA network to detect prognostic biomarkers in cancer via indication of upregulated / downregulated gene states....
10 August 2017 279 1 View
How can the inhibition of ATP driven pumps help one to deliver the therapeutics across the BBB reaching the tumor site successfully and which efflux pump should be blocked for rapid delivery .
18 June 2017 6,780 0 View
What are some of the best approaches to find out functional modules in gene expression data .
27 May 2017 9,501 3 View
How does herpes simplex virus hijack the retrograde transport machinery to infiltrate the brain and cross blood-brain barrier to deliver appropriate therapeutic for brain injuries.Is it reversing...
17 May 2017 1,976 2 View
Is it possible to rotate the current spin states of electrons of cancer cells with some kind of non-elastic collision via high intensity photon particles to stop cancer progression in last stage.
12 November 2016 4,604 3 View
Can quasi-static control systems be used to reconstruct Gene regulatory networks from microarray data.
28 August 2016 6,481 1 View
How can Gene Networks be reverse engineered with Bayesian Computing or SVM's.
28 August 2016 3,760 1 View
How can we reverse engineer Stochastic Gene Networks of Cervical cancer system to study its dynamics more closely and inhibit the cancer progression at the transcriptional level.
30 July 2016 8,855 2 View
I have miR-222-3p, miR-125b-5p in case of OAS3 as our gene of interest, and TRAFD1 as Transcription Factor all in case of humans as host. All these are forming a 3-node Feed-forward loop (i.e.,...
01 January 1970 8,708 0 View
