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Many studies showed high dose of curcumin induces ROS formation and caspase medicated apoptosis in both fibroblasts and keratinocytes which should in theory make curcumin unfit for the treatment...
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Most phenolic compounds in the nature are present in glycoside forms.But I don't see any paper mention that curcumin is in glycoside form in nature. All I hear is it is not water soluble so they...
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it is a bit confusing to see both TLR4 agonsits and antagonists induce IL10 expression. Studies clearly say that TLR4 activation(by LPS) results in upregulation of IL10(IL10 would in turn result...
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some research suggests that the glycan stay attached to its aglycon part while it binds to the receptor(s), in fact the glycan residues itself bind to receptor helping in longer receptor...
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