15 Questions 24 Answers 0 Followers
Questions related from Noha G Mohamed
i want know the role of sodium acetate in the acetylation of primary aromatic amine using acetic anhydride. the reaction mechanism doesn't explain it.
05 May 2021 9,750 5 View
I want to make docking using Autodock and both receptor and ligand are proteins. i followed the usual steps of docking small molecule ligand but when I reach to docking step, an error message says...
31 July 2020 4,050 9 View
I need a free program to analyze H-NMR spectrum. Any recommendations?
30 May 2020 1,659 2 View
Hello All im trying to make docking using autodock and i have two questions 1 - i want know what is the use of "set up covalent map" option and how i select the proper atom? 2 - when i compare...
18 September 2018 4,899 0 View
I want to use Pymol to view an enzyme - drug interactions. i could only view the hydrogen bonds but how can i vew other types of interactions like hydrophobic, metal bonds and ion - water bridge?
24 July 2018 2,247 7 View
Hello im trying to make docking with autodock 4.2.3 and the autogrid command always show error message saying ( C:\Windows\system32\autogrid4.exe: ERROR: Grid data file needs the extension...
17 April 2018 8,107 10 View
I want to make high throughput screening by MOE and when i made the validation, RMSD value was very high. I changed the following parameters: Placement, rescoring1, refinement and rescoring2 and...
21 February 2018 1,243 4 View
Rigid protein docking deals with the protein / receptor as rigid structure while in induced fit docking receptor sidechains are allowed to flex during refinement of the poses when should i use...
15 December 2017 6,697 2 View
Reflux in pyridine (as reported) or in dioxane (using few drops of pyridine or sodium carbonate as catalyst) was not successful
11 November 2015 8,823 4 View
Reflux alcoholic solution of 5-substituted 3-amino1,2,4-triazole with benzaldehyde or 4-chloro benzaldehyde using acidic catalyst (glacial acetic acid or HCl or H2SO4) for 12 hours not give any...
09 February 2015 3,985 21 View
Im trying to synthesize naphthyridinyl amino triazole from naphthyridinyl hydrazide by reaction with S-methylisothiourea sulfate and sodium hydroxide but the preciptated product have same RF of...
27 July 2014 9,879 3 View
The mixture contains nalidixic acid dissolved in chloroform then triethylamine and ethyl chloroformate were added and stirred for 30 minutes. Methanol was added to synthesize methyl ester. How to...
11 February 2013 3,155 8 View
Bromination of nalidixic acid
12 January 2013 6,895 0 View
Docking of ATP synthase of mycobacteria
19 December 2012 3,676 16 View
i synthesized aromatic schiff base from 3-aryl-5-amino 1,2,4-triazol. How can i know it is E or Z using another tool than X ray crystallography.
01 January 1970 3,138 6 View
