Narayan Acharya

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Questions related from Narayan Acharya

Is folic acid cytotoxic to human kidney cells ?

My group is interested in folic acid cytotoxicity in human kidney cells. Are there any reports available showing toxic effects of FOLIC ACID as in the case of mice kidneys? Any insights will be...

20 October 2020 2,577 3 View

What is the minimum concentration of Folic acid that shows cytotoxic effects against HK-2 cells in vitro ?

Our group is involved in renal fibrosis research. In order to figure out the mechanisms of renal fibrosis, we used a Folic acid animal model. Just to check relevancy with the human kidney, we want...

20 October 2020 9,859 0 View

Could you please suggest expert opinions on how to reduce mortality of C57BL/6J mice for folic acid (125mg/kg bwt.)model of renal fibrosis study ?

I am doing a renal fibrosis study using folic acid model of C57BL/6J mice. Our initial dose was 250mg/kg bwt. which we reduced to half (125mg/kg bwt) once we saw more animal death after injection....

29 February 2020 2,277 0 View