Nagavenkata Satyasrinu

3 Questions 1 Answers 0 Followers

Questions related from Nagavenkata Satyasrinu

How can i separate 3,5-Dimethylphenol and it's positonal isomer by using reverse phase hplc?

I got usp resolution 1.1 between main peak and it's positional isomer on C8/PFP mixed mode column.any suggestions to improve the resolution

22 March 2020 5,657 3 View

Carry over problems ?

I am using X-Bridge C18 column with 25cmx4.6mm,5µ MPA: 0.02M Ammonium dihydrogen phosphate with pH 2.0 with OPA +0.1mL of TFA in 1000 mL of water MPB:MPA:ACN(20:80) Time % of A % of B 0...

03 March 2018 6,234 3 View

I am facing a problem about carryover ?

While developing a reverse phase HPLC method for Edoxban Tosylate drug substances and it's related substances ,carry over is observed is from blank injection with area around 2000 which is...

03 March 2018 3,991 4 View