Muhanad Ali

6 Questions 11 Answers 0 Followers

Questions related from Muhanad Ali

How do I find release profile fitting for different mathematical models?

Im trying to associate cumulative drug release profile with a mathematical model. How is this achieved?

18 December 2017 4,078 2 View

How can I accelerate solidification of PLGA micropsheres using the solvent evaporation method W/O/W emulsion?

I want to accelerate the microsphere solidification to reduce the drug partitioning into the external aqueous phase and increase the encapsulation efficiency.

21 March 2016 4,161 1 View

I am experiencing very low encapsulation efficiency using the solvent evaporation double emulsion method and I'm not sure why?

Does anyone have any recommendation on the best possible method? Or, the reason behind this? I have tried adjusting the pH of the aqueous phases but that hasn't changed anything. I look forward...

18 March 2016 6,890 1 View

What is the best method to check the encapsulation efficiency of PLGA spheres?

There are many protocols available, but unfortunately the solvent used give a high background reading and therefore i can not detect my drug. Which method is more useful when measuring the...

24 February 2016 1,375 5 View

What is the best method to achieve high encapsulation?

I'm using water in oil in water (W/O/W) double emulsion. I was wondering what is the best method to encapsulate a hydrophilic compound? Should I dissolve the compound in the aqueous phase then...

01 February 2016 369 2 View

What is an alternative solvent to DCM which does not have a high emission at 360 nm?

I want to quantify my drug using HPLC, but the the solvent im using (DCM) is interfering with my readings at 360nm. What is an alternative solvent to use that is not excited at 360 nm? Thanks.

29 January 2016 1,304 4 View