Max Saito

6 Questions 6 Answers 0 Followers

Questions related from Max Saito

METHOCEL™ (HPMC) F4M and no changes in different dissolution medias

I am using METHOCEL™ (HPMC) F4M for my formulation and tested in Simulated: Gastric Fluid (pH 1.2), Intestinal Fluid (6.8), Pulmonary Fluid (7.4) and Ringer Fluid and did not see relevant changes...

03 July 2017 1,479 1 View

The mechanism of action of most fucoidans are inhibition of Anti-thrombin and Heparin Cofator II?

I am studying a new type of fucoidan that show prolonged time for the aPTT tests and do not have show any interference on PT test.But, if fucoidans inhibits AT and Heparin Cofactor, in PT test we...

14 January 2017 8,829 2 View

Can I use this modified protocol to observe derivative/P-selectin interaction?

Use an immulon 1B microtiter plate Incubate with Recombinant Human PSGL-1/CD162 Fc Chimera Protein Wash and add activate platelets with my derivative that blocks P-selectin Wash and add Goat...

02 January 2016 7,594 1 View

Any suggestions on Eudragit RS-100, Hemostasis and Hemocompatibility?

Anyone know about assays that can be done with Eudragit-RS100 and coagulation/aggregation tests?Eudragit RS-100 is a cationic non-biodegradable polymer insoluble in water.I know that is soluble in...

02 January 2016 5,130 0 View

Does anyone know a cationic polymer like Eudragit rs-100 for LNC, but biodegradable?

I will start to work with LNC and need to use a cationic polymer, like Eudragit-RS100. But, we will spray drie these LNCs to pulmonary route. As we know, Eudragit RS-100 is not a good candidate...

25 November 2015 1,055 2 View

[Pulmonary Admnistration in Rats] New methods versus old methods

Recently, I tried to administer pulmonary formulation in rats and in literature with an modified method comparing with several others. Using the Penn Century (1), instillation (2), cannulation via...

01 January 1970 4,551 0 View