Max Knier

7 Questions 6 Answers 0 Followers

Questions related from Max Knier

How do Glycosaminoglycans/Proteoglycans attract water to the ECM for compression resistance?

I thought its because of the many sulfat groups which they contain ? So they are negativly charged in some way ? Please correct me if im wrong.

05 March 2022 3,570 5 View

Which molecules (glycosaminoglycan/proteoglycan) are most important in the extracellular matrix of the eye?

Especially when it comes to hydrating the eye/conjunctiva/sclera and prevent it from getting reddish and showsing reddish veins like in this picture.

06 January 2022 5,026 4 View

Red conjunctiva / sclera and instability of almost all soft tissues (mainly dense connective tissue), especially in relation to compressing forces?

In particular, the tissue seems to have lost its ability to withstand compression. The soft tissue of the body seems to be compressed by gravity and its own weight. Can someone link articles that...

27 December 2021 899 0 View

How often are new proteoglycans and glycosaminoglycans synthesized in the human extracellular matrix ?

Did some research already but didn´t find any real answers so far. I think it differs from tissue to tissue but a approximate answer about how often and at what intervals new proteoglycans and...

21 December 2021 4,933 2 View

Which molecules stabilize the extracellular matrix (connective tissue) and give it the ability to resist compressive forces?

I thought it are glycosaminoglycans and proteoglycans but it would be interessting to know exactly which proteoglycans and glycosaminoglycans are the most important and which genes encode these...

14 December 2021 4,684 3 View

Are there any articels about repairing a mutation in col2a1 gen via chrispr/base editing?

And leads the correction to the produce of healthy collagen II ?

29 May 2021 3,491 0 View

What type of collagen is most common in the human skull / face sutures?

Which collagen type is most common and could lead to unstable sutures if the gen which encodes this collagen is mutated ? Thank you in advance

21 May 2021 5,003 4 View