Kunal Tewari

3 Questions 2 Answers 0 Followers

Questions related from Kunal Tewari

Any ideas of how you can protect secondary amine with BOC on solid phase?

I have been trying to protect terminal secondary amine with BOC group however with normal Boc2O (4-6 equivalents) with catalytic amount of DMAP, Chloranil test still shows positive. The last...

01 December 2017 951 0 View

How to Boc protect secondary amine on solid phase

I have a monomer to be attached to my peptoid on rink amide MBHA resin having both primary and secondary amino groups. The primary amine is Fmoc protected and the secondary amine requires Boc...

27 July 2017 5,978 2 View

Anyone working with N-FMOC-ethylenediamine HCl faced any difficulties with it in respect to its solubility?

So far i have tried NMP, DCM, DMF but usually it tends to precipitate out after few minutes. I usually add required quantity of base to the solvent to neutralise the salt followed by stirring the...

26 July 2017 1,792 0 View