Krishan Kumar Saini

3 Questions 1 Answers 0 Followers

Questions related from Krishan Kumar Saini

How to know if a small molecule transcriptionally regulating or decreasing the mRNA stability by Actinomycin-D experiment in RT-qPCR?

We have been working with a small molecule that suppresses the expression of some survival genes mRNA. we have done an Actinomycin-D experiment with and without the small molecule along with...

07 July 2021 1,824 1 View

What are the roles of RELA/p65 in regulating the apoptosis in different aspects i.e. in survival, apoptotic or anti-apoptotic and cytosolic role?

Hello Everyone, I have a bioactive small molecule that target MDA-MB-468 (TNBC cell line) cells and induces robust cytotoxicity, but not effective in neither TNBC nor other normal and cancer cells...

04 February 2021 430 2 View

How to prevent sorting of a protien to mitochondria?

Hello everyone. i've a protien that found in cytosol and mitochondria. the mitochonrial form of this protien is different from cytosolic protien that themRNA of the mitichondrial protien has a...

13 May 2018 361 1 View