Karin Vadovičová

6 Questions 9 Answers 0 Followers

Questions related from Karin Vadovičová

Any evidence against ? Ketamine + other serotonergic agents activate IPN-> MRN -> claustrum-> SWA+ unconsciousness?

Any data, findings against this circuit idea ? I have idea that ketamine and serotonergic agents activate via 5-HT 2A (or other serotonergic receptors) on IPN which activates the IPN output,that...

29 February 2024 5,344 0 View

MHb -> IPN -> MRN -> serotonin -> claustrum activation -> SWA + unconsciousness. Any proofs against the MRN causing anesthesia + memory replay + SWS ?

I seek multiple feedback and discussion which can disprove my idea that: Activation of MHb (by mu-opioids, nicotine, acetylcholine, ATP and glutamate) and disinhibition of MHb by...

29 February 2024 7,884 0 View

Any views about what does anteromedial thalamic nucleus (AM) do ?

I found strong prefrontal projections to the lateral habenula in humans, with high fibre tract density around AM. It is possible that the PFC-LHb projections form collaterals in AM. AM is known...

11 November 2014 7,900 7 View

Is the impulsivity linked to the motivational D1 loop of ventral striatum attenuated by serotonin?

We explain how is motivational state controled by dopamine and serotonin in D1 loop of ventral striatum (VS). It is known that dopamine enforces the impulsivity, motivation and drive via...

24 September 2014 348 4 View

Ketamine in anesthesia -> new circuit idea, ready for discussion

found ketamine activation of slow wave sleep and anesthesia circuit. ketamine + serotonin -> IPN -> MRN -> claustrum + hippocampus -> slow wave oscillations -> anesthesia + slow wave sleep +...

01 January 1970 2,177 0 View

Opiates -> MHb -> IPN -> PAG ? new respiratory depression circuit

I am curious to get feedback, comments: on new idea how medial habenula causes respiratory depression when activated by mu opioids. I think that MHb activates interpeduncular nucleus, which...

01 January 1970 5,979 0 View