Jordan B Jahrling

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Questions related from Jordan B Jahrling

Could anyone provide a potential explanation for how one could have increased triglycerides but decreased body fat?

I am working with a compound and have observed an overall decrease in the body fat percentage in my mice, but our blood work shows a significant increase in blood levels of triglycerides. Is...

21 January 2016 9,375 12 View

Can anyone tell me why urethane and alpha chloralose are used in combination for cerebral blood flow studies?

I will be performing cerebral blood flow studies in mice and the majority of publications on this subject say they utilize both urethane and alpha chloralose delivered IP as anesthetic. I...

20 October 2015 5,956 5 View

Does anyone have a protocol for quantifying IHC images in ImageJ?

I want to quantify fluorescence and co-localization in microscopy images from some IHC experiments using ImageJ, but am unsure of how to do so. If anyone has a detailed protocol or could direct me...

01 May 2015 10,003 24 View

Could anyone recommend brain regions to look at to investigate tight junctions?

I am planning to do an IHC study from mouse coronal brain sections and will be looking at various tight junction proteins. I of course realize that endothelium is present throughout the brain but...

12 February 2015 10,033 6 View

Is there a known drug or chemical that can be given to mice to induce blood-brain barrier leakage?

I am looking at the effects of a compound on blood-brain barrier integrity. Preliminary results indicate that the compound improves tight junction expression in aged mice. I am looking for a way...

21 November 2014 8,069 8 View