Jacob Sode

4 Questions 8 Answers 0 Followers

Questions related from Jacob Sode

How to calculate the amount of phenotype variance explained by a few SNPs?

I'm working with a validation dataset, testing 7 previous SNP association. A few of these SNPs is validated as associated with a binary phenotype of interest. Now I want to calculate the amount...

26 April 2016 9,504 1 View

FDR Correction for multiple testing in genetic association studies?

In a genetic association study we’re performing multiple analyses. We have decided to correct the multiple testing with false discovery rate (FDR) method. Let me give an overview of the study In...

07 August 2015 2,759 4 View

Why do I get uncharacteristic real-time PCR amplification curve?

We have performed real-time qPCR on plasma samples for specific miRs (RNA purified, RT, pre-amplified). For one of the miRs we got this uncharacteristic amplification curve with a "pre-top", a...

05 June 2015 7,416 3 View

How can one increase image quality of LD triangle plot in Haploview?

In haploview I have made an LD plot for the purpose of including it in a manuscript/poster. However, the image is very pixelated and of low quality. I cannot see where to increase pixels per inch...

05 March 2015 4,331 7 View