Hanna Schumacher

6 Questions 4 Answers 0 Followers

Questions related from Hanna Schumacher

What are overall assumptions for comparing two enzymes of the same class consisting of more or less different amino acids?

I do research on genetic code and aminoacyl-tRNA-synthetase (aaRS) evolution. An aaRS consists eihter of 18, 19 or 20 amino acids. Are there biological rules or findings that allow the assumption...

14 February 2019 5,835 7 View

Which simulations of genetic code evolution do exist?

Are there simulations that... - simulate changes in the tRNA pool? - simulate flexizymes? - simulate aaRS? I did a lot of research but didn't find practical approachs on the role of these three...

23 January 2019 8,863 1 View

Does a flexizyme or sth. similar exist that can charge a tRNA with two different amino acids?

Is there any aaRS like construct that charges either... ...one tRNA with one out of two amino acids or ...two tRNAs with one amino acid each but not the same amino acid. Further more there is...

12 November 2018 3,089 0 View

How long does an Aminoacyl-tRNA-Synthetase live? How often is it reproduced?

For my current project I do a lot of research about aaRS but didn't find answers to these questions yet. I am happy about any information about the lifecycle of these enzymes.

06 November 2018 2,902 2 View

Why do we have three-base-codons when it is possible to translate four- or five-base-codons?

Five-base codons for incorporation of nonnatural amino acids... When tRNAs can have three, four and five base anticodons, why do only tRNAs with three-base-anticodons exist in today's translation...

01 January 1970 7,312 15 View

Did aaRSs first appear in a cell or protocelll or earlier?

Is there knowledge about this? What are the hypotheses? Thanks in advance.

01 January 1970 3,072 1 View