Hai V. Ngo

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How to inactivate the excess DCC from DCC/DMAP coupling agents?

I am making a conjugation of R1-COOH and R2-OH by estertification using DCC/DMAP. Unfortunately, the R2 also contains COOH group. So after activation of R1-COOH, how can I quench the unreacted...

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How to perform the coupling of two carboxylic groups?

I am trying to conjugate two materials having both carboxylic group. Is there any available method or intermediate for effective conjugation. Many thanks for your kind suggestions.

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