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Questions related from Flora Dai
I genotyped several SNPs of a gene and investigated the association of all possible two and three marker haplotypes with the disease. In this case, how do you adjust the ' P' value for multiple...
29 July 2013 103 5 View
I found a case control sample's genomic inflation factor by Eigenstrat analysis. Now I have genotyped one SNP in this sample and calculated the p value for the allelic association test. How can I...
23 March 2013 3,619 2 View
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17 March 2013 8,253 1 View
After my population based case control study, I did power analysis to indicate that the negative result was not caused by underpower. Should I input risk allele frequency for power test? Should I...
31 January 2013 1,860 0 View
When using Genetic Power calculator, besides inputting the high risk allele frequency A (I used the hapmap data), the value of genotype relative risk for AA and Aa were required. How could I get...
30 November 2012 6,217 2 View
The combination can enlarge sample size. However is there a valid way to do it?
21 November 2012 7,363 2 View
In PLINk, T/NT can be shown, but how can I calculate the allele frequencies in affected and unaffected groups in a family sample?
13 November 2012 6,021 0 View
How could i find out if the allele frequency given by dpsnp is based on forward or reverse?
05 November 2012 1,019 1 View
The family sample includes families comprising one or more than one affected offspring. When both parents were not available in a family, one or more unaffected siblings were included in this...
31 October 2012 296 3 View
I want to choose several SNPs in a gene for association studies,with previous positive results firstly. But if these SNPs are not tag SNPs, should I consider the LD? if so, which is better to...
27 September 2012 2,418 6 View
