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Questions related from Fawzi Bokhari
Why would someone choose to perform siRNA HTP over small molecule inhibitors HTP or vice versa? If you perform an siRNA screen and end up finding a target and then develop a small molecule...
04 April 2014 2,789 2 View
If not, do you think is it possible to simulate this in order to predict which genes might be real hits, of course before the real in vitro experiments?
11 November 2013 6,778 1 View
1) What are the potential checkpoints that are activated when an obvious mitotic exit delay occurs and why mitotic exit delay differs from cell line to another and from cells treat it with a...
11 November 2013 7,495 1 View
An interesting issue, although the end of the story is the same - cell death. However, how can we check if we have triggered any of them? I know how to ensure that we have activated the apoptotic...
03 March 2013 8,301 32 View
The Early genes 6 and 7 (E6/E7) of the HPV cause perturbation of the p53 and Rbp, respectively. This phenomenon is well-noticed in the SV40 where the large T antigen (TAg) abrogate the functions...
03 March 2013 3,200 3 View