Dr Scott Burtis

5 Questions 7 Answers 0 Followers

Questions related from Dr Scott Burtis

Will taking exogenous arginase inhibitors shift M1/M2 macrophage balance to a more M1 phenotype?

M1 macrophage pathways favor NOS conversion of arginine into citrulline and NO. M2 pathways favor arginase conversion of arginine into ornithine and urea. I am wondering if taking exogenous...

26 September 2017 9,168 0 View

Can wrist temperature be used as an accurate assessment of circadian disruption?

Salivary cortisol levels seem to be the gold standard but typically only show one day's worth of statistics. Would recording wrist (or other) temps over an extended period be a more accurate way...

13 June 2017 8,833 5 View

Would supplementing with selenomethionine upregulate prostaglandin D2 sythase expression?

Upregulating PGD2 synthase decreases transformation of astrocytoma II to III, and I am curious if selenoproteins would block the transformation by upregulating PGD2 and/or PGD2 synthase.

28 January 2015 1,871 0 View

What effect would targeting VEGF with an antiangiogenic have in someone who has increased expression of HIF-2?

CBS (cystathione beta synthase) is a fairly common single nucleuotide polymorphism, and can result in increased expression of HIF-2 alpha thus increasing tumorogenesis. Treatment with...

07 December 2014 7,458 2 View

Does anyone have any insight into what a magnesium bolus would do to vascular permeability in a patient taking a VEGF inhibitor?

Avastin can affect vascular permeability, normal BBB restrictions on Mg diffusion would thereby be bypassed opening the possibility of excitation and possibly seizures in those prone,

24 November 2014 7,673 5 View