Dorian Foster

8 Questions 3 Answers 0 Followers

Questions related from Dorian Foster

How can I calculate the logP of hyaluronic acid or other complex molecules?

I have been previously using https://www.molinspiration.com/services/logp.html to calculate log P for materials I use in my drug delivery research where it makes calculations based on canonical...

28 March 2024 9,760 0 View

How can I determine the appropriate dialysis pore size for my metal nanoparticles?

I am looking to preform a release study on iron oxide particles from a drug carrier, we have always used dialysis devices for other types of drug studies but I am slightly worried about the size...

19 February 2024 5,363 4 View

How can I get MRI phantom images of nanoparticles that are prone to aggregate/settle?

I am working with the polymeric modification of iron oxide particles and I am trying to get phantom MRI images at each stage of modification to comment on how the contrast effects are altered by...

27 November 2023 9,798 2 View

Is there a way to set specific temperature ramping rates on an Ohaus 7000 Guardian?

I am trying to synthesize Iron oxide nanoparticles via thermal decomposition and have read that temperature ramping rate plays a significant role in the reaction -- we did not have these...

19 October 2023 9,591 0 View

How can relaxivity be calculated from image intensity of an MRI phantom image?

I took MRI phantom images at various concentrations of iron (100, 50, 25, and 12.5 ug/mL) for my iron oxide based contrast agent system. The images came out as expected, with more darkening...

28 July 2023 2,008 3 View

What surfactants are the best for preventing aggregation in metal nanoparticles?

I have thus far been unable to get DLS characterizations of some ultrasmall iron oxide nanoparticles that I purchased commercially and I believe it is due to high rates of aggregration, especially...

11 June 2023 1,860 4 View

How can I get relaxivity measurements from a standard large animal MRI machine?

I am looking to characterize a contrast agent I'm developing for relaxivity. At my university, I have access to a Esaote Vet-MR Grande. Is it possible to get relaxation time measurements from this...

01 June 2023 3,789 3 View

How can I get accurate DLS measurements on my amine functionalized iron oxide nanoparticles?

I ordered 3nm iron oxide particles, amine functionalized, commercially. I am trying to use DLS to measure hydrodynamic diameter to later confirm additional coatings and functionalizations. I have...

26 April 2023 569 6 View