Doohee Lee

4 Questions 2 Answers 0 Followers

Questions related from Doohee Lee

Does cholesterol change the phase transition temperature of liposome?

Hi. I want to know whether cholesterol change the phase transition temperature of liposome. The phase transition temperature of DPPC is 41 ℃ . If I add 30% of cholesterol, does phase transition...

26 June 2020 2,688 0 View

If drug/lipid ratio increased in liposome, can encapsulation efficiency be affected?

Hi, I want to increase drug to lipid ratio when making liposome. I wonder if drug encapsulation efficiency (encapsulated drug/ total drug) can be affected by this ratio. For example, Comparing...

04 September 2019 8,457 7 View

Can I measure encapsulation effiiciency of liposome by dialysis?

I want to find encapsulation efficiency of drug in liposome. Can I separate non-encapsulated drug by dialysis and calculate E.E from them? I use DSPC as phospholipid and N-acetylcysteine which is...

29 August 2019 2,057 5 View

Can sucrose, which is used to lyophilize the liposome, affect cell viability in vitro experiment?

I'm going to freeze-dry for the storage of liposome. In order to lyophilize the liposome, sucrose should be added. Will the sucrose affect the cell viability when in vitro experiments? because in...

01 August 2019 1,095 2 View