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Questions related from Dina Morshedi
Using DLS, we found that the average size of our fabricated nanoliposome decreased from 180 to 140 nm, however we did not find any reason for it. The drug was a monoclonal antibody.
16 January 2023 6,786 3 View
Some reports recently show that A-beta or alpha-synuclein can be entrapped with neuronal cells by endocytosis and using some special receptors and cargoes. Why neuronal cells have this potential....
29 December 2016 4,079 3 View
I want to have a cell line with high content of a-synuclein. I have looked at many reports which in them two different systems were used to over-express of a-synuclein. Does any one know which...
18 July 2015 924 5 View
The free enrgy for unfolding (H2O), against pH has the max point near pI. In this pH average of charges is zero. But what the axact relationship is between the stability and pI,. We know all...
10 May 2015 1,301 4 View
In preformulation process , assessing deamidation should be done in short term. In deamdation reactions ( we have fiffernt reactions), Asn usually is the main residue to be converted. Does Asn...
24 April 2015 1,509 3 View
We are working with a protein to induce fibrillation forms. Our FTIR (deep peak at 1624 qnd 1695) results and AFM images (twisted long fiberils) confirmed fibril formation. In spite of these...
17 September 2014 3,849 9 View
We are working with a small molecule with low solubility in aqueous solutions and it must be dissolved in DMSO before added to Tris buffer. We loaded it on a nanoparticle and now we want to follow...
24 April 2014 6,687 2 View