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Questions related from Devendra Lingojwar
I have purified PEG modified albumin by ion exchange chromatography. Final product 96KD analyzed on analytical FPLC with >99% purity. My PEG reagent if 30KD and Albumin is 66 KD, after...
12 May 2016 8,457 10 View
In an autosomal recessive genetic disorder i.e. sickle cell anemia in a two kids family, if the status of grandfather is not known whereas grandmother is carrier. Status of indexed patient’s...
11 September 2015 4,201 5 View
In transgenic sickle mice, if hematocrit is low, how tissue oxygenation will progress. Is it low tissue oxygenation or high tissue oxygenation ?
06 August 2015 5,331 1 View
Two most important pathogenesis of SCD patients are acute hemolytic anemia and vaso occlusive crisis. Hemolytic anemia is due to hemolysis of sickle cells. As polymerized hemoglobin S attached to...
27 May 2015 740 5 View
To my knowledge, there is no direct marker in SCD patients which can be studied for vaso occlusive crisis. Most of the markers such as cytokines and other inflammatory molecules are indirect and...
22 May 2015 5,211 5 View