Darwin Reyes

9 Questions 23 Answers 0 Followers

Questions related from Darwin Reyes

How to differentiate strength of Target-DNA Aptamer interaction versus DNA Aptamer-Complementary DNA hybridization?

We will be developing competitive lateral flow aptasensors for a small molecule target. However, we are concerned about the strength of the DNA aptamer- target interaction versus the interaction...

01 March 2018 2,647 3 View

Is it possible to have two different types of diffusion mechanism in the same types of drug delivery systems varying only in polymer concentration?

I am using 1%, 1.5% and 2% sodium alginate solutions and reacting them with calcium lactate to encapsulate salbutamol. In the Korsmeyer-Peppas plot, the 1st and 3rd formulation follows super case...

20 February 2013 6,352 4 View

Possible causes of low % drug encapsulation efficiency.

I'm doing salbutamol-loaded calcium alginate microparticles. Can you suggest reasons why I got low % drug encapsulation efficiency?

16 February 2013 5,060 6 View

UV Visible spectra of salbutamol sulfate.

I have scanned a 5mg solution of salbutamol (as sulfate) in pH 7.4 PBS from 200nm - 400nm in order to obtain its absorption spectra. Based on the certificate of analysis, its maximum absorption is...

11 February 2013 8,799 21 View

What are the possible applications of inorganic nanomaterials?

I've been looking at some papers regarding the synthesis and characterization of different inorganic materials and I am becoming interested with this topic.

02 February 2013 2,181 6 View

What is the best drying method to do in order to get low-moisture content alginate hydrogels?

Im only doing air-drying. Can you suggest other methods that will produce low-moisture content alginate hydrogel without altering the properties of the drug loaded inside the polymeric matrix.

28 January 2013 2,936 1 View

What does it mean when there is a large amount of moisture in drug-loaded calcium alginate microparticles?

Does it mean that the content of the polymer is mostly water? How about the drug? How can it be explained chemically?

25 January 2013 3,938 2 View

Do I need to heat the solution when preparing an alginate solution?

I am working on my undergrad research, which is about calcium alginate microparticles as drug delivery systems. I had a hard time preparing the solution because of the viscous nature of the...

08 December 2012 4,905 15 View

What is the best gauge size to use in the ionotropic gelation method?

I will be using the ionotropic gelation method in preparing the drug - loaded calcium alginate microparticles

25 November 2012 6,218 3 View