Is it possible to have inhibition of DNA fragmentation with z-vad-fmk but not cleavage of PARP?

I am working with a synthetic compound that can induce DNA fragmentation in MCF-7 and MDA-MB-231 cells. When I co-incubate with z.vad.fmk, fragmentation is only partially inhibited in MCF-7 cells...

24 April 2013 2,575 6 View