Ben Webb

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Questions related from Ben Webb

Does furin cleavage of SARS-CoV-2 S1/S2 occur upstream, during or downstream of the open/closed conformations of the RBD?

Hi there, As part of my dissertation, I am trying to understand how the open/closed conformational changes of the RBD contribute to SARS-CoV-2 binding to neuropilin-1. My main question is if furin...

24 November 2020 1,235 4 View

Transient receptor potential ion channel vanilloid 1 (TRPV1) inhibitors

The protocol for isolating N-type calcium channel in DRGs, as described by Moutal et al. 2020, describes using the inhibitors " Nifedipine (10 μM, L-type); ω-agatoxin GIVA (200 nM, P/Q-type);...

01 January 1970 1,523 0 View

What is SARS-CoV-2's RNA polymerase template sequence?

In aid of a project that I am currently completing for UCL, I need to know the exact RNA sequence of SARS-CoV-2 that the RNA-dependent RNA Polymerase binds to. To clarify, I know that ORF1a and...

01 January 1970 6,747 4 View