Avadhesh Kumar Singh

3 Questions 6 Answers 0 Followers

Questions related from Avadhesh Kumar Singh

What is the possible explanation for plasticity of CD25loFoxp3+ Treg cells?

Reportedly this small population is dynamic and pathogenically converts into Th17 cells. CD25lo population, but not CD25hi, shows plasticity towards Th17 cells.

04 February 2014 9,400 3 View

Can the cells positive for invariant alpha chain but negative for beta chain be considered as invariant NKT cells?

The cells identified by monoclonal antibody 6B11, binds to CDR3 loop of alpha chain, are reportedly considered as iNKT cells. However, it is quite possible that a few cells may be 6B11+ but TCR...

30 January 2014 8,383 7 View

Since DAMPs recognize a range of molecules, do they need a particular receptor to activate inflammasomes?

Damage associated molecular patterns (DAMPs) recognize sterile signals generated by stress by the affected cells. Sterile signals include a range of molecules.

14 June 2013 278 1 View