Alice Thomson

4 Questions 3 Answers 0 Followers

Questions related from Alice Thomson

Tau2 and I2 in meta-analysis?

I am currently performing a meta-analysis, and I am using the The Restricted Maximum Likelihood ("REML") method to estimate tau2. However for one of my subgroups (33 studies) I have a tau2 of 0,...

29 March 2023 5,192 3 View

META- analysis risk of Bias - Case/control observational study which frame work should I use?

I am currently carrying out a meta-analysis on metabolite levels in Case vs controls and I am trying to understand which risk of Bias assessment to use. Cochrane suggest ROBINS - however this is...

09 November 2022 7,515 3 View

Controls for CRISPR/Cas9 reporter line FACS?

I am planning to sort transgenic hESC lines based on reporter lines fluorescent markers, to see if FACs sorting of progenitors results in greater Da yields. For my control study I have included a...

17 November 2020 8,758 1 View

How does FACs sort for multiple markers in immunolabeled cells?

I am currently designing a research proposal for isolation of dopaminergic neurones progenitors by FACs (after immunolabbeling for 3 different intracellular proteins). I wondered whether this...

10 November 2020 8,543 5 View