16 Questions 7 Answers 0 Followers
Questions related from Ahmed Shaker Ali
Simple tutorial for MetaXL or any other free software for meta-analysis for beginners.
19 February 2025 8,113 1 View
I am currently working on the development of a mucoadhesive microemulsion spray designed for use within the oral cavity. The formulation aims to incorporate both water-soluble natural compounds...
23 September 2024 1,523 0 View
Dear researchers and scientists I did a partial docking experiment to learn the basics of using an internet server. (Seamdock). Two ligands, the first is known to inhibit the target protein and...
05 June 2023 8,649 3 View
I tried to do molocular docking of okadiac acid ( 125 atom ) as ligand , Calcenurin A as macromolocule using PyrX but error is generated the same with Seamdoc ?
01 June 2023 3,192 1 View
I did molocular docking of a small liberary of falvinoid ligands about 700 molocules , traget macromolocule Clacenurin A 4OR9. Using PyrX. Protein was prepared by Discovery studio . I get few...
26 May 2023 8,217 2 View
I am bigner in molocular docaking, I use the free avialble sofware as IGentek , seamDock . I need to load the ligands as a batch ?
05 May 2023 3,281 3 View
Unfortunately, most data are missed for antiviral e.g Remidisvir i want to speculate plasma/ lung ?? or any alternative measure We estimated Vd of this antiviral drug from published data dose....
15 July 2020 2,566 5 View
I tried to submit an article to this journal which is ranked as Q1 but when I follow the link after submitting and review process before payment we discover another similar name , Advances in...
28 February 2020 611 2 View
we are investigating the additive effect of Sirilomius in compination with a safe drug in ameliorating the Dss induced colitis in rats we aim to identify autovagy ( mTOR ) my quesion what...
26 February 2019 4,190 0 View
we studied the effect FK506 in animal model for DSS we obtained good results IL-6 , IL-IB , TN-alfa all attenuated , histologist finding support good remission of induced colitis . we need...
17 January 2019 8,286 0 View
I realized that studies on the effect of Ramadan fasting on Pharmacokinetics of commonly monitored drug or high alert drugs are limited . Of course extrapolation of animal studies is questionable...
07 April 2018 9,135 0 View
I am interested in GABA and other neurotransmitters.
30 December 2013 4,349 2 View
Ivermectin well-known drug - gave promising results in the treatment of Covid 19, although there is a concern, based on the fact that the concentration of free drug in the blood ( with safe...
01 January 1970 1,134 15 View
Is there clinical studies regarding impact of obesity on PK of immunosuppressant commonly used in solid organ transplantion
01 January 1970 9,522 2 View
Dear colleague, I am writing to seek your expertise in molecular docking to identify the potential protein target of our novel quinoxaline derivative against Candida albicans. I would be grateful...
01 January 1970 4,966 0 View
we know that remdesivir disappears from the blood within 3 hr after IV , biotranformed to metabolites it is accumulated in PBMCs. with sustained level up to 24 hr or more My question is these...
01 January 1970 8,475 0 View
