Ahmed Agiba

6 Questions 106 Answers 0 Followers

Questions related from Ahmed Agiba

How to calculate the dissolution efficiency (DE) and mean dissolution time (MDT)?

I would like calculate the dissolution efficiency (DE) and mean dissolution time (MDT) based on data obtained from in-vitro, comparative dissolution and calculations of f1 (difference) and f2...

20 February 2020 9,582 6 View

How to stabilize Azilsartan Medoxomil in a combination with Chlorthalidone in tablet formulation?

I try to formulate a tablet dosage form of Azilsartan Medoxomil and Chlorthalidone. I face a number of challenges, mainly for Azilsartan Medoxomi, in Assay, Dissolution and Stability. Obviously,...

02 August 2018 7,386 6 View

Do anyone know the best method(s) to evaluate the neuroprotection of dietary polyphonels in both in-vitro and in-vivo cellular models?

I have read some research articles talking about using rat pheochromocytoma (PC12) cells for investigating the neuroprotective effects of dietary polyphenols and...

25 February 2018 5,429 1 View

Can anyone help me on this "the polydispersity indices (PDIs) of the prepared liposomes were ranging from 1.55±0.38 and 3.66±2.34"?

While I was measuring PDI of the prepared liposomes, I had values, ranging from 1.55±0.38 and 3.66±2.34. It is known that PDI should have values below 0.7. But in my case, I had values > 0.7....

02 May 2017 1,562 3 View

I have a problem in the formulation of Dioctahedral Smectate Sachets?

For Industrial Purposes I am preparing a powder for reconstitution for oral use (sachet) containing: - Dioctahedral Smectate - Pectin - Kaolin as active ingredients. The ratio of Pectin to Kaolin...

20 February 2017 6,613 2 View

Comparative Dissolution of Cefpodoxime 200 mg F.C.T with Cefpodoxime Proxetil Tablets (Innovator)?

when comparing comparative dissolution of our product (Cefpodoxime 200 mg F.C.T) with Cefpodoxime Proxetil Tablets (Innovator), and according to USP; at pH 3.0 (Glycine), our product showed 45%...

16 November 2016 3,796 14 View