I was planning to perform a chemical reaction between a secondary alcohol and 2-bromoethylamine using NaH. Based on the mechanism of the reaction and previous literature, I am supposed to react NaH first with the alcohol before the addition of 2-bromoethylamine. Should I protect the amine before I proceed with the reaction to have a primary amine in my product, or it won't do any harm to leave it unprotected? I tried to look through previous literature, but I couldn't find much information regarding the use of the amine in williamson ether synthesis.

More Ahmed Ibrahim's questions See All
Similar questions and discussions