I was wondering if I fear condition my rats, and then train them in Morris Water Maze (spaced training), will the rats show weaker or no long term spatial memory? I tried to look for relevant literature, but could not find many papers directly addressing this sort of question. If I missed them, could someone send me those papers? Thank You.
From your question it's not really clear, do you aim to test such a hypothesis or to avoid unwanted effects of one task on another?
Fear conditioning in rats can be quite stressful, so the effects of stress modulators (corticosterone, noradrenaline) can definitely affect learning in the next task. But the effects will depend on shock intensity, the timing of each task etc.
If you could be more specific I'd love to provide more literature recommendations.
https://psycnet.apa.org/record/1998-10128-011
Hi Deepti, although i'm not an expert on that topic here are some review articles that may be helpful. If you would make you question more detailed it will be more easier to give you an answer. Greetings!!!
Links:
https://psycnet.apa.org/doiLanding?doi=10.1037%2F0735-7044.121.2.335
https://psycnet.apa.org/doiLanding?doi=10.1037%2Fa0028453
Article The rat perirhinal cortex: A review of anatomy, physiology, ...
Article Effects of stressors in adolescence on learning and memory i...
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