"The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardise any mission to Mars, according to a new study led by researchers from UCL"
https://www.sciencedaily.com/releases/2024/06/240611130413.htm#:~:text=Summary%3A,led%20by%20researchers%20from%20UCL.
https://www.nature.com/articles/s41467-024-49212-1
https://newatlas.com/space/kidneys-space-travel-mars/
https://www.newsweek.com/mars-mission-astronauts-kidney-damage-space-radiation-1913817
Yes. Astronauts because of the thrill of exploration, rich people partly for the thrill, and partly as a way to show off how insignificant it is to them to throw away tens of millions of dollars for whatever they want to do. Astronauts, of course, are depending on NASA and similar agencies to figure out ways to reduce the dangers of space travel, and space tourists aren't really out "there" long enough for it to significantly increase their risk of disease, because if the required physical shows that they suffer from a problem that MIGHT be significantly affected, they aren't allowed to go, regardless of how much money they offer (those providing the rides don't want even one customer to die, as it would be bad for business).
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