Why traditional (protein/antigen based) vaccines don't trigger a cell mediated immune response ?

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If Proline and Glycine are incompatible with helical structural conformation of protein, why do these amino acids are abundantly found in Collagen ?

It's said that Proline and Glycine amino acids are incompatible with helical structure and form kink in the helix, but why do Proline and Glycine are abundantly found in the collagen ?

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error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

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error in modelling model in Abaqus

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MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

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MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

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fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

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fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View

John Schloendorn

Outside of Moderna's pitch deck, of course they do. A lot of details play together here. Start with a recent review paper...

Deivasigamani Balaraman

My based on the work plan in protein trigger in case of immunology study it is very fought job... protein based vaccines can't trigger in cell mediated immune response time consuming more and we cannot timely workout or trigger in cell responses...till the work is going on.....