Production of ethanol from mixture of lignocellulose substrates is overlook, whats the reason behind not applying substrates in mixture for ethanol production.
The association of proteins with lignocellulose degraded products results in protection of the tertiary structure of proteins, which increases resistance to long term denaturation.
To reduce pre-treatment process costs, as the sugars are strongly bind with lignin and not freely available to microorganisms as compared to other sources
Also, the pretreatment process doesn't act in the same way for the different lignocellulosic materials.
Being honest, your question is very interesting since the biomass could be classified according to the effective pretreatments. For example, if in one country you have 3 different lignocellulosic materials but if the 3 are agricultural residues, then it would be to evaluate if the pretreatment you want to use works in the same way, if so, they could be mixed.
On the other hand, the transport model should be considered, for example, there may be two lignocellulosic substrates that are far from each other and then it could be more profitable to install two bioethanol production plants instead of one since such it sees the cost of the transport of lignocellulosic material is higher in the long term.
The prtreatment process for different kind of lignocellulosic biomass may differ. The substrates showing showing good results with a particular pretreatment process could be tried as mixture for ethanol production.