We have several Sunrise Science SC (synthetic complete) dropout mixtures in our lab, and I recently went through them after coming back from lockdown. We keep our SC dropouts in a desiccator inside our 4*C cold storage unit, and several had spoiled when we returned to the lab a few weeks back when our institute opened back up. They were all years away from the expiration date on the package (most were set to expire in late 2022 or early 2023) but smelled AWFUL (like animal excrement awful) and had turned from smooth white powder to brown, chunky, clumpy, stinky mixtures. Oddly enough, all the dropouts that had gone bad were those with leucine as one of the dropped out amino acids. Anyone else experience a similar issue? Wondering why only a select few had spoiled and not all of them. Thank you!