I'm agree with their opinion towards vascular factor disorders in the MS lesions. Why do explore only venous vascular net? As for my experience, majority of MS-patients have a multivascular reasons in patogenesis of MS-focuses. I believe, that adequate vascular correction of the cerebral arterio-venous balance leads to the decreasing of neurological deficits. In our practice we have some no-walking MS- patients, which began realized their self serving program slowly step-by-step due to our long-term combine courses with vascular therapy and individual neurorehabilitation approach. There are nearly 5-6 etipatogenetical hemodynamical patterns of MS-arterio-venous disorders at extra- and intracranial levels.
Article Detailing intra-lesional venous lumen shrinking in multiple ...
http://www.nationalmssociety.org/Research/Research-News-Progress/Research-News/CCSVI
J Neurol Neurosurg Psychiatry 2009;80:392-399 doi:10.1136/jnnp.2008.157164
Research paper
Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis
Open Access
P Zamboni1,
R Galeotti1,
E Menegatti1,
A M Malagoni1,
G Tacconi1,
S Dall’Ara1,
I Bartolomei2,
F Salvi2
+ Author Affiliations
1
Vascular Diseases Center, University of Ferrara, Ferrara, Italy
2
Department of Neurology, Bellaria Hospital, Bologna, Italy
Professor P Zamboni, Vascular Diseases Center, University of Ferrara, 44100 Ferrara, Italy; [email protected]
Received 2 July 2008
Revised 7 November 2008
Accepted 10 November 2008
Published Online First 5 December 2008
Abstract
Background: The extracranial venous outflow routes in clinically defined multiple sclerosis (CDMS) have not previously been investigated.
Methods: Sixty-five patients affected by CDMS, and 235 controls composed, respectively, of healthy subjects, healthy subjects older than CDMS patients, patients affected by other neurological diseases and older controls not affected by neurological diseases but scheduled for venography (HAV-C) blindly underwent a combined transcranial and extracranial colour-Doppler high-resolution examination (TCCS-ECD) aimed at detecting at least two of five parameters of anomalous venous outflow. According to the TCCS-ECD screening, patients and HAV-C further underwent selective venography of the azygous and jugular venous system with venous pressure measurement.
Results: CDMS and TCCS-ECD venous outflow anomalies were dramatically associated (OR 43, 95% CI 29 to 65, p
Thank you very much for the excellent information. I've been doing the USD-investigation of venous cerebral blood flow for almost 30 years. Indeed, there are a clear hemodynamic patterns of arterial insufficiency and venous stasis both at extracranial and intracranial levels in patients with multiple sclerosis. With regard to spinal level, I do not yet managed to explore it using ultrasound. Although, the vertebral venous network overload is often the problem in this category of patients. It is not in accordance with the wording of vein stenosis - I regard as it's more functional hypoplasia, which can be neglected in the individually selected treatment approach. Regarding the study of cerebrospinal arteries - the idea is interesting. Perhaps, further research in this area will shed light on the problems of cerebral vascular disorders in patients with lateral amiotrofic sclerosis, because we obtained significant improvements swallowing and speech during specific vascular therapy in these patients.
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