Interesting! May be the toxic principle is not in the epidermis and the whole seed passes thru the digestive track unopened like many other seeds. The inner constituents may be responsible.
Another aspect could be fungal growth! on oil seeds when cut open, asperigillus like fungi attack and one example is aflatoxins!
By crushing the seeds into powder, more of the active component(s) is disintegrated making more of it ingestible such that the toxic effect now observed may be due to exposure to toxic concentrations of the components.
It may also be necessary to consider how the powdering of the seed was done, the process(es) involved may have resulted in the release of toxic components of the seed.
thank about your attention, but I found a herb with properties like the cotton seed wich name is Ngella sativa.Do you know some plants with this properties????
Please highlight what exact properties you are referring to; that will help me to be able to answer your question better
Property that I need: plants that Complete seed is beneficial but powder seed has toxicity property.
I have not yet come across such plants, but I will try to make enquiries and inform you if i find such..
Interesting! May be the toxic principle is not in the epidermis and the whole seed passes thru the digestive track unopened like many other seeds. The inner constituents may be responsible.
Another aspect could be fungal growth! on oil seeds when cut open, asperigillus like fungi attack and one example is aflatoxins!
yes ,maybe you are true Mr.Maringanti,but My goal is to utilize this property,please give me an idea for beginning a research.
The observation made by Dr. Maringanti is very interesting but should be also considered the possibility of a postinhibitine mechanism. As happens with cyanogenic glycosides or glucosinolates. When the cellular structure is lost the enzymes may catalize reactions on substrates which were previously separated due to the cellular compartimentation.
Yes Dr.Alessandro! You are right. I did not mention. It is a common mechanism one must be aware. The enzymes may generate new moieties that did not exist!
Ali Farhang: Your aim is not clear to me sir. Could you clarify? How do you want to utilise such property? Where and how? Then we could discuss more.
So far, I have found that fruits like apples, apricot, pears, cherries, peaches, cherimoya, and ackee have seeds that can be medicinal but also also toxic. You can do more search on these. I will still see what I can help you find out
Dr Maringanti thanks for the support. It may also be interesting to investigate the nature of the substance responsible for this toxicity.
Dr. Maringanti and Dr. Venditti I want to know that can we utilize from this property in medical?and is useful this property or its just harmful?and I have another question that if we eat cotton seed, we will not poisoned,why? our gastric acid can remove the seed coat,so why we will not poisoned?
Dear Dr Farhang, I may answer you from a phytochemical point of view so first I would try to separate and identify the components of the ethanolic extract of seeds. Then is possible to test the activity of the single fractions. Where was recognized glycosides, the activity could be performed before and after treating the fractions with a beta-glucosidase. In this manner is possible to correlate an eventual toxicity to the aglicone moiety. For a possible application I suppose that should be first evaluated from a pharmacologic point of view and more experimental data are necessary.
On toxicity of cotton seeds you may check what is available in literature: e.g. this is a review
Toxic substances in cottonseed meal and its microbial detoxification
Wang, Chunfang; Li, Quanfeng; Cheng, Maoji
From Siliao Yanjiu (2011), (3), 18-19.
In case of seeds - if we won't crush the seed with our teeth, it will go through our intestine in one piece. Seeds are "designed" to stay intact in the stomache. That's why many fruits are "meant" to be eaten - seeds will travel in animal even several kilometers and they will be put on the ground in a package of quite good fertilizer :)
I have heard that several seeds may be poisonous after crushing - e.g. taxus. As I remember seeds won't do harm if they are not crushed. But benefits are unknown.
I think the Gossypol is the name of constituents which is present there in cotton seed. And it might be there in testa so only if chewed or powdered than it is released. Because testa part is not digested by our stomach. Same way seeds of apple if we chew them it is toxic as it contains cynogenetic glycoside.
Cottonseed oil is refined, bleached and deodorized to eliminate the gossypol level and then used and Cottonseed soapstocks are obtained as byproduct and it is used as animal feed additives and usually contain much lower gossypol concentrations than do whole cottonseeds. Some animals able to detoxify gossypol by formation of stable complexes with soluble proteins in the lumen preventing its absorption and some animals can not and hence toxicity is observed.
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