Hello, Dennis.

Here are mRNA results of VDR from different analysis. And you can get more information at http://www.genecards.org/cgi-bin/carddisp.pl?gene=VDR&keywords=vitamin,D,receptor#expression

Hope it will be helpful.

Hi Dennis.. Human brain contain many vit D receptors. Vit D probably has important role in maintaining cognitive function. It acts as a neurosteroid through its receptor and has important role in many neurohumoral pathways. Experimental studies have shown similarity of human brain with brain of rodent in terms of vit D receptors.. Thanks

For the past two decades, vitamin D has been increasingly recognized as a potent neurosteroid with multiple actions in the brain. Based on the well-described endocrine actions of vitamin D, it is metabolized to its hormonal form 1,25(OH)2D3 in various organs such as the gut and kidney and, in this form, it enters the brain via the blood brain barrier to act directly on cells containing its nuclear receptor, the vitamin D receptor (VDR). However, it appears now also likely that an autocrine/paracrine system within the nervous system underlies the cerebral actions of vitamin D in brain. In the latter case, the presence of the various key enzymes and receptors is a prerequisite.

Journal of Steroid Biochemistry and Molecular Biology (2017), http://dx.doi.org/10.1016/jJsbmb.2017.09.008