I thing you should first understand what is CloudSim and what is Hadoop. You are comparing two different things. A Simulator vs A File System

Quote Ved Yadav's follow-up comment "Which one is better for analysis of semantic interoperabilty of Healthcare Data in Cloud Computing context?"

I suggest Hadoop for the analysis of semantic interoperabilty of Healthcare Data in Cloud Computing context. The following book "Hadoop: The Definitive Guide, Storage and Analysis at Internet Scale, 3rd Edition" provides the guideline for the analysis of the US National Climatic Data Center (NCDC) Weather Data.

http://shop.oreilly.com/product/0636920021773.do

CloudSim vs Hadoop for cloud environment analysis is similar to OPNET vs Linux testbed for TCP/IP traffic analysis (an example is given below to illustrate OPNET vs Linux testbed)

(1) For academic research, CloudSim is better.

CloudSim is a pretty handy simulator with java API, which lets any researcher create a cloud environment of his/her own requirement.

The CloudSim simulator is so flexible that it lets the user customize/configure the cloud environment from a granularity level of specifications of a particular virtual machine to communication between multiple cloud vendors. The simulator also lets the user plug-in his/her own policies.

Network simulator example (OPNET): The following paper used OPNET for TCP/IP traffic analysis

OPNET simulation for API-RCP(TCP Congestion Control):"Design of Adaptive PI Rate Controller for Best-Effort Traffic in the Internet Based on Phase Margin," IEEE Transactions on Parallel and Distributed Systems, 18(4), April 2007, pp. 550-561.

http://www.researchgate.net/publication/3301176_Design_of_Adaptive_PI_Rate_Controller_for_Best-Effort_Traffic_in_the_Internet_Based_on_Phase_Margin

Review, Comments, and extensive evaluation on API-RCP:"Improving the Efficiency and Fairness of eXplicit Control Protocol in Multi-Bottleneck Networks", Elsevier Computer Communications, 2013.

http://www.sciencedirect.com/science/article/pii/S0140366413001059

(2) For industrial application, Hadoop is better.

Hadoop is a real cloud platform which can help the cloud service provider in providing cloud computing services to the cloud users.

Real network example (Linux testbed): The following paper built Linux testbed for TCP/IP traffic analysis

Linux testbed implementation for API-RCP(TCP Congestion Control): "An Implementation and Experimental Study of the Adaptive PI Rate Control Protocol," Proceedings of IEEE workshop on High Performance Switching and Routing (IEEE HPSR), Paris, France, June 2009.

http://www.researchgate.net/publication/224611517_An_implementation_and_experimental_study_of_the_Adaptive_PI_Rate_Control_Protocol

(3) CloudSim is a simulation tool to emulate a cloud platform, while Hadoop builds a real cloud platform.

Using CloudSim simulator, the user does not need to take too much attention about the hardware details and can concentrate on the algorithm design.

Using Hadoop to build a real cloud platform, the user needs to consider the hardware details.

The simulation cost of Hadoop is much expensive than that of CloudSim.

(4) CloudSim vs Hadoop == Simulated Clouds vs real Clouds

Quote from the following official website of CloudSim: "Specifically in the case of Cloud computing, where access to the infrastructure incurs payments in real currency, simulation-based approaches offer significant benefits, as it allows Cloud customers to test their services in repeatable and controllable environment free of cost, and to tune the performance bottlenecks before deploying on real Clouds."

http://www.cloudbus.org/cloudsim/

Quote from the following official website of Apache Hadoop: "The Apache Hadoop software library is a framework that allows for the distributed processing of large data sets across clusters of computers using simple programming models. It is designed to scale up from single servers to thousands of machines, each offering local computation and storage."

http://hadoop.apache.org/

(5) Quote from Ved Yadav's question "cloud environment analysis in the context of healthcare dataset":

If your analysis aims at academic research and publication, and your available hardware resource is limited, CloudSim is better choice due to its cheaper hardware cost;

If you aims at provide a cloud service for the hospitals in the future, you need to use Hadoop which can provide the real-time cloud environment analysis in the context of healthcare dataset.

Article Design of Adaptive PI Rate Controller for Best-Effort Traffi...

Conference Paper An implementation and experimental study of the Adaptive PI ...

how to install CloudSim on my Windows 7 Desktop PC. Give some easy steps to install.

CloudSim is not an executable, it is a library and you have to add the the CloudSim jar in your class-path while compiling. The easiest way is to install netbeans or eclipse and than create a new java project and Google how to add external libraries in a project and than you are good to go start by executing some of the cloudsim examples available on their website .

@yang hong ..

Which one is better for analysis of semantic interoperabilty of Healthcare Data in Cloud Computing context ?

URGENT

Pls, which simulator can handle algorithms in both grid and cloud at the same time?