Which methods is mostly used to handle audio files?

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Don Knox

There's a balance to be struck between compression ratio and resulting audio quality/integrity. I'd suggest a lossless format like FLAC if the audio quality is paramount. Otherwise use a lossy format like Ogg Vorbis and reduce the bit rate to a level that maintains *acceptable* quality.

Jem Mathew

compression a file with out changing its bit rate is better.......