I want to determine the molecular weight distribution (MWD) of a polymer (polyurea) by dissolution in HFIF (hexafluoro isopropanol) and GPC (gas permeation chromatography). Do you have experience in this type of analysis? I am trying to find the right concentration of polymer into the solvent for the analysis.
Thank you in advance
Hi Elia, I would start with a 0.1% w/v sample solution. You should have a clear solution. Maybe you also can try a combination of HFIP and m-cresol.
Thank you for the information, I will try with this concentration. Why the combination with m-cresol? Isn't the solubility of the polymer lower with the combination of the two? Regards
Hi Elia, a co-solvent can improve the solubility of your polymer (but not in every case). Here is the method trail and error the best way to test the solvent conditions.
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