In green revolution this NPK theory caused major loss in soil fertility and ultimately the agriculture productivity/unit fertiliser use has gone down in most of the green revolution areas. I am taking example of India where the production enhanced due to vertical and horizontal spread in irrigation facility and yes, NPK fertilisers caused sudden jump in production in the initial 15-20(because of inherent fertility of land- no micro nutrient deficiency ) years, at the cost of soil health and water productivity .However, it has been experienced during last two decades (1990s onward) that there is minimal increase in productivity despite increase in graph of fertiliser use. On the other side in drylands (60% part of agriculture) where fertilisers use is minimum and more use of organic inputs, the productivity in the good rainfall years surpasses the conventional system, and the yield of conventional system (clearly visible in cotton) in the poor rainfall years is much below than organic system. There may be some other reasons for emphasising the NPK use rather than the agro-ecological need. Also application of NPK fertilisers there is possibility of risk addition in the agriculture production in the changing climate scenario.
May be optimum use of water integrate with organic manure application is the key of sustainable agriculture in long term.